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2.2.7Cancer

AQA GCSE Biology (8461), Higher tier · Organisation › Animal tissues, organs and organ systems

Practise Cancer. 11 exam-style questions plus unlimited generated ones on this subtopic, at up to four difficulty levels, with full mark schemes and a progress tracker. Free, no account needed.

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Complete the sentence.
Cancer is the result of changes in cells that lead to ____________ growth and division.
uncontrolled
The statements describe how a malignant tumour forms and spreads. They are not in the correct order.
A Cells break off from the tumour and enter the blood.
B Changes in a cell cause it to grow and divide in an uncontrolled way.
C The cells are carried to another part of the body.
D A tumour forms.
E The cells divide to form a secondary tumour.
Write the letters in the correct order.
B, D, A, C, E

Sample questions

Written for this site in the style of AQA exam questions. They are not taken from real past papers.

Question 1Easy4 marks
Cancer is a non-communicable disease.
(a) Complete the sentence.
Cancer is the result of changes in cells that lead to ____________ growth and division.[1]
(b) Which statement describes a benign tumour?
Tick (✓) one box.[1]
  • It is contained in one area, usually within a membrane.
  • It spreads to other parts of the body in the blood.
  • It forms secondary tumours.
  • It invades neighbouring tissues.
(c) What type of tumour invades neighbouring tissues and spreads to other parts of the body?[1]
(d) Give one lifestyle risk factor for cancer.[1]
Show the answer and mark scheme
(a) Answer: uncontrolled
  • uncontrolled
(b) Answer: It is contained in one area, usually within a membrane.
(c) Answer: malignant
  • malignant
(d)
  • smoking / obesity / drinking alcohol / exposure to UV (sunlight or sunbeds) / poor diet
Question 2Medium5 marks
Tumours can be benign or malignant.
(a) Give two differences between benign tumours and malignant tumours.[2]
(b) A patient has a malignant tumour in the lung. Doctors later find a secondary tumour in the brain.
Explain how the secondary tumour formed.[2]
(c) Some people have a genetic risk factor for a type of cancer.
What is meant by a genetic risk factor?[1]
Show the answer and mark scheme
(a)
  • benign tumours are contained in one area / within a membrane, malignant tumours invade neighbouring tissues
  • malignant tumours spread in the blood to form secondary tumours, benign tumours do not spread
(b)
  • cells broke off the lung tumour and were carried in the blood (to the brain)
  • they divided (uncontrollably) in the brain to form a new tumour
(c)
  • an inherited gene / allele that increases the likelihood of developing the cancer
Question 3Hard6 marks
A tumour can usually be detected by a scan when it contains about 1 × 109 cells.
In one type of tumour, the number of cells doubles every 60 days.
229 = 5.4 × 108 and 230 = 1.07 × 109
(a) A tumour starts from one abnormal cell.
How many doublings are needed before the tumour contains at least 1 × 109 cells?[1]
(b) Calculate the time taken for the tumour to reach this size.
Give your answer in years.
1 year = 365 days[2]
(c) Explain why it is important to detect malignant tumours while they are small.[2]
(d) Suggest one reason why a real tumour might take longer than your calculated time to reach 1 × 109 cells.[1]
Show the answer and mark scheme
(a) Answer: 30
  • 30
(b) Answer: 4.9 years
  • 30 × 60 = 1800 (days)
  • (1800 ÷ 365 =) 4.9 (years)
(c)
  • before cells break off and spread in the blood to form secondary tumours
  • so the tumour is easier to remove / treat successfully
(d)
  • some tumour cells die / the doubling time increases as the tumour grows / the tumour's blood supply limits its growth

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