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4.3.1.8Antibiotics and painkillers

AQA GCSE Combined Science (8464), Higher tier · Biology › Infection and response › Communicable diseases

Practise Antibiotics and painkillers. 14 exam-style questions on this subtopic, at up to four difficulty levels, with full mark schemes and a progress tracker. Free, no account needed.

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Revision notes

What antibiotics and painkillers can and cannot do, why antibiotics do not work on viruses, why it is hard to make drugs that kill viruses and why antibiotic-resistant bacteria are a concern. Questions are usually short 'explain why' items, sometimes with data.

Grade by grade

What you need to be able to do, from the first marks up to the top grade.

  1. 3
    State what antibiotics doAntibiotics, such as penicillin, kill infective bacteria inside the body, curing bacterial diseases.
  2. 3
    State what painkillers doPainkillers treat the symptoms of a disease but do not kill pathogens.
  3. 4
    Explain why antibiotics don't treat viral diseasesAntibiotics kill bacteria but cannot kill viruses.
  4. 5
    Explain why specific antibiotics are neededDifferent antibiotics kill different bacteria, so the antibiotic must match the bacterium causing the disease.
  5. 6
    Explain why antiviral drugs are hard to developViruses reproduce inside body cells, so drugs that kill them are likely to damage body tissues too.
  6. 7
    Explain why antibiotic resistance is a concernResistant strains are not killed by the antibiotic, so infections become hard to treat and the strains can spread.

Notes

Antibiotics

  • Antibiotics, such as penicillin, are medicines that cure bacterial diseases by killing infective bacteria inside the body.
  • Specific bacteria should be treated with specific antibiotics: an antibiotic that kills one type of bacterium may not kill another.
  • Antibiotics have greatly reduced deaths from infectious bacterial diseases.
  • Antibiotics cannot kill viruses, so they do not help with viral diseases such as colds, flu or measles.

Antibiotic resistance

  • Some strains of bacteria have become resistant to antibiotics: the antibiotic no longer kills them. This is of great concern.
  • Infections caused by resistant strains are hard to treat and can spread, e.g. MRSA and some strains of the bacterium that causes gonorrhoea.
  • To slow the development of resistance, doctors should not prescribe antibiotics for viral or minor infections, and patients should complete the course of antibiotics.

Painkillers and other medicines

  • Painkillers (e.g. aspirin, paracetamol) and other medicines, such as cough medicines, treat the symptoms of a disease.
  • They do not kill pathogens, so they do not cure the disease. The immune system still has to destroy the pathogen.

Why viral diseases are hard to treat

  • Viruses live and reproduce inside the body's cells.
  • It is difficult to develop drugs that kill viruses without also damaging the body's tissues.
  • So most viral diseases are treated with painkillers and other medicines to ease the symptoms while the immune system destroys the virus. A few drugs can control viruses, e.g. antiretroviral drugs for HIV.

Cheatsheet

  • Antibiotics kill bacteria inside the body, e.g. penicillin
  • Antibiotics do NOT kill viruses
  • Use the specific antibiotic for the specific bacterium
  • Painkillers treat symptoms but do not kill pathogens
  • Resistant strain = bacteria that are not killed by an antibiotic
  • Drugs that kill viruses are hard to develop: viruses are inside cells, so the drugs may damage body tissues

How to answer each type of question

Explain why antibiotics are not prescribed

2 marks4
  1. Say what type of pathogen causes the disease.
  2. Say that antibiotics do not kill that type of pathogen (viruses).

Example. A patient with a cold asks for antibiotics. The doctor refuses.
Explain why.

Show the model answer
Colds are caused by a virus (1). Antibiotics do not kill viruses, so they would not help (1).

Compare painkillers and antibiotics

2 marks4
  1. Painkillers: relieve symptoms, do not kill pathogens.
  2. Antibiotics: kill the bacteria, so they cure the disease.

Example. A person with a bacterial throat infection takes painkillers and a course of antibiotics.
Describe the different effect of each type of medicine.

Show the model answer
Painkillers relieve the symptoms, such as pain, but do not kill the bacteria (1). Antibiotics kill the bacteria causing the infection, so they cure it (1).

Explain why drugs against viruses are hard to develop

2 marks6
  1. Say where viruses live and reproduce: inside body cells.
  2. Say that drugs that kill them would also damage body cells or tissues.

Example. Explain why there are far fewer drugs to treat viral diseases than to treat bacterial diseases.

Show the model answer
Viruses live and reproduce inside the body's cells (1). So it is difficult to kill the viruses without also damaging the body's cells and tissues (1).

Data: resistant bacteria

3 to 4 marks7
  1. Percentage change = change ÷ original value × 100.
  2. Explain the concern: the antibiotic does not kill resistant bacteria, so infections are hard to treat.
  3. Add the consequence: serious illness or death, and the resistant bacteria can spread.

Example. In a hospital, infections caused by a strain of bacteria resistant to an antibiotic rose from 25 to 40 in one year.
(a) Calculate the percentage increase.
(b) Explain why the increase in resistant bacteria is a concern.

Show the model answer
(a) 40 − 25 = 15 (1); 15 ÷ 25 × 100 = 60% (1)
(b) The antibiotic does not kill the resistant bacteria, so these infections are hard to treat (1). Patients may become seriously ill or die, and the resistant bacteria can spread to other patients (1).

Shortcuts and memory tricks

  • AntiBiotics are anti-Bacteria. They do nothing to viruses.
  • Painkillers kill pain, not pathogens.
  • Three 'anti' words: antibiotic (medicine, kills bacteria), antibody (made by white blood cells, binds to antigens), antitoxin (neutralises toxins).

Where marks are lost

  • Saying antibiotics kill viruses or cure colds and flu.
  • Saying painkillers cure a disease or kill pathogens.
  • Saying the person, or their body, becomes resistant to antibiotics. It is the bacteria that become resistant.
  • Mixing up antibiotics (medicines) and antibodies (made by white blood cells).
  • Answering 'why are antiviral drugs hard to develop?' with 'antibiotics don't work on viruses'. The reason is that viruses are inside body cells, so drugs that kill them may damage body tissues.

Exam technique

  • Check which type of pathogen causes the disease in the question before you recommend a treatment.
  • Use 'resistant' for bacteria and 'immune' for people. 'The bacteria become immune' does not get the mark.
  • In percentage change calculations, divide by the original value and show your working.

Quick recall

Cover the answers and test yourself. The app has these as flashcards that come back just before you'd forget them.

Doctors use different types of medicine to treat diseases. Name one antibiotic.
Penicillin
Antibiotics and painkillers are both used to treat illness, but they work in very different ways. Give one example of a painkiller.
Paracetamol (or ibuprofen / aspirin)

Sample questions

Written for this site in the style of AQA exam questions. They are not taken from real past papers.

Question 1Easy5 marks
Doctors use different types of medicine to treat diseases.
(a) What do antibiotics do?
Tick (✓) one box.[1]
  • Kill bacteria inside the body
  • Kill viruses inside the body
  • Make the body produce antibodies
  • Reduce pain but do not kill pathogens
(b) Name one antibiotic.[1]
(c) Many people with a cold take painkillers, such as paracetamol.
Explain why painkillers do not cure a cold.[2]
(d) Give the reason why doctors do not prescribe antibiotics for a cold.[1]
Show the answer and mark scheme
(a) Answer: Kill bacteria inside the body
(b) Answer: Penicillin
  • penicillin
(c)
  • painkillers only treat the symptoms
  • (they) do not kill the pathogen / virus
(d)
  • colds are caused by viruses and antibiotics do not kill viruses
Question 2Medium7 marks
A patient has a throat infection caused by a bacterium. A doctor prescribes an antibiotic and tells the patient to take a painkiller as well.
(a) Explain why the doctor must choose an antibiotic that is effective against the specific bacterium causing the infection.[2]
(b) Explain the different roles of the antibiotic and the painkiller in treating the patient.[2]
(c) The use of antibiotics has greatly reduced deaths from bacterial diseases.
Give one reason why scientists are concerned about the future use of antibiotics.[1]
(d) It is difficult to develop drugs that kill viruses.
Explain why.[2]
Show the answer and mark scheme
(a)
  • different antibiotics kill different types of bacteria / specific bacteria must be treated with specific antibiotics
  • (otherwise) the bacteria would not be killed and the infection would not be cured
(b)
  • the antibiotic kills the bacteria (causing the infection)
  • the painkiller relieves the symptoms / pain but does not kill the bacteria
(c)
  • strains of bacteria resistant to antibiotics are emerging / becoming more common
(d)
  • viruses live / reproduce inside the body's cells
  • (so) drugs that kill viruses may also damage the body's cells / tissues
Question 3Hard9 marks
A doctor prescribed an antibiotic for a child with a bacterial infection.
The daily dose is 25 mg of antibiotic per kg of body mass, split into 3 equal doses. The child has a mass of 18 kg.
(a) Calculate the mass of antibiotic in each dose.[2]
(b) The antibiotic is supplied as a liquid containing 250 mg of antibiotic in every 5 cm3.
Calculate the volume of liquid the child should be given in each dose.[2]
(c) The child also had a painful ear and a high temperature, so was given a painkiller.
The maximum daily dose of the painkiller is 60 mg per kg of body mass. The painkiller liquid contains 120 mg in every 5 cm3.
Calculate the maximum volume of painkiller liquid the child can be given in one day.[3]
(d) Explain why the child was given a painkiller as well as the antibiotic.[2]
Show the answer and mark scheme
(a) Answer: 150 mg
  • 25 × 18 (= 450 mg per day)
  • 450 ÷ 3 = 150 (mg)
(b) Answer: 3 cm3
  • 150 ÷ 250 × 5
  • 3 (cm3)
(c) Answer: 45 cm3
  • 60 × 18 = 1080 (mg)
  • 1080 ÷ 120 (= 9) × 5
  • 45 (cm3)
(d)
  • the painkiller relieves the symptoms / pain / high temperature
  • (but) it does not kill the bacteria, so the antibiotic is needed to cure the infection

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