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4.6.1.5DNA structure

AQA GCSE Biology Foundation (8461), Foundation tier · Inheritance, variation and evolution › Reproduction

Practise DNA structure. 2 exam-style questions on this subtopic, at up to four difficulty levels, with full mark schemes and a progress tracker. Free, no account needed.

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DNA is a polymer of nucleotides, and the order of its bases codes for the order of amino acids in a protein. This is in GCSE Biology only, not in Combined Science.

Key facts

  • Nucleotide = sugar + phosphate + one base
  • Four bases: A, C, G, T
  • DNA strand: alternating sugar and phosphate, with a base on each sugar
  • 3 bases = the code for 1 amino acid

Notes

DNA is a polymer of nucleotides

diagram
  • DNA is a polymer made from repeating units called nucleotides.
  • Each nucleotide is a common sugar and a phosphate group, with one of four bases attached to the sugar.
  • The four bases are A, C, G and T. You do not need to know the structures of the bases.
  • Each long strand has alternating sugar and phosphate sections, with a base attached to each sugar.
  • one nucleotideAphosphatesugarbaseTACGGTsugar–phosphatebackbone3 bases (a triplet)= 1 amino acidnext triplet= next amino acid
    DNA is a polymer of nucleotides. Every three bases code for one amino acid.

The genetic code

  • A sequence of three bases is the code for one particular amino acid.
  • The order of bases controls the order in which amino acids are assembled to make a particular protein.

How to answer each type of question

Describe the structure of DNA

3 to 4 marksGrade 5
  1. Say DNA is a polymer of repeating nucleotides.
  2. Describe a nucleotide: sugar, phosphate and one of four bases (A, C, G, T).
  3. Describe the strand: alternating sugar and phosphate, with a base on each sugar.

Example. Describe the structure of a DNA molecule. [4 marks]

Show the model answerHide the model answer
DNA is a polymer made of repeating nucleotides (1). Each nucleotide contains a sugar, a phosphate group and a base (1). There are four different bases: A, C, G and T (1). Each strand has alternating sugar and phosphate sections with a base attached to each sugar (1).

Don’t lose marks

  • Saying each base codes for an amino acid. It takes a sequence of three bases.
  • Saying a nucleotide contains amino acids. A nucleotide is a sugar, a phosphate and a base.

More tips

Memory tricks

  • Number of amino acids = number of bases ÷ 3.

Exam technique

  • Write 'a sequence of three bases codes for one amino acid', not 'three bases code for a protein'.

What each grade needs

What you need to be able to do, from the first marks up to the top grade.

  1. Grade 4
    Name the four bases in DNAThe four bases are A, C, G and T.
  2. Grade 5
    Describe the structure of a nucleotideA common sugar and a phosphate group, with one of four bases attached to the sugar.
  3. Grade 5
    Describe DNA as a polymer of nucleotidesLong strands of alternating sugar and phosphate sections, with a base attached to each sugar.

Quick recall

Cover the answers and test yourself. The app has these as flashcards that come back just before you'd forget them.

DNA is a polymer. Give the letters of the four bases found in DNA.
A, C, G and T

Sample questions

Written for this site in the style of AQA exam questions. They are not taken from real past papers.

Question 1Easy5 marks
DNA is a polymer.
(a) What are the repeating units that make up DNA called?
Tick (✓) one box.[1]
  • Amino acids
  • Fatty acids
  • Glucose molecules
  • Nucleotides
(b) What does each of these repeating units contain?
Tick (✓) one box.[1]
  • A phosphate group and an enzyme
  • A sugar, a phosphate group and one of four bases
  • An amino acid and a base
  • Glucose and a fatty acid
(c) Give the letters of the four bases found in DNA.[1]
(d) How many bases code for one amino acid?[1]
(e) What makes up the long strands of a DNA molecule?[1]
Show the answer and mark scheme
(a) Answer: Nucleotides
(b) Answer: A sugar, a phosphate group and one of four bases
(c) Answer: A, C, G and T
  • A, C, G, T (all four)
(d) Answer: 3
  • 3 / three
(e) Answer: Alternating sugar and phosphate sections
  • alternating sugar and phosphate (sections / groups)
Question 2Medium6 marks
{fig} shows part of one strand of a DNA molecule.
[object Object]
(a) Name the parts labelled X, Y and Z in {fig}.[3]
(b) What is the unit inside the dashed box labelled W called?[1]
(c) Describe how the nucleotides are joined together to make one strand of DNA.[2]
Show the answer and mark scheme
(a) Answer: X: phosphate (group); Y: sugar; Z: base
  • X: phosphate
  • Y: sugar
  • Z: base
(b) Answer: A nucleotide
  • nucleotide
(c) Answer: The sugar of one nucleotide is joined to the phosphate of the next, forming an alternating sugar–phosphate strand with a base attached to each sugar
  • sugar of one nucleotide joins to the phosphate of the next / alternating sugar and phosphate
  • a base is attached to each sugar

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